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KMID : 1084220150220020127
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Journal of Rheumatic Diseases
2015 Volume.22 No. 2 p.127 ~ p.131
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A Case of Palmoplantar Pustulosis Present in the Daughter of a SAPHO Syndrome Patient
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Choi Ji-Young
Kim Jae-Min
Song Ran
Lee Yeon-Ah
Lee Sang-Hoon
Yang Hyung-In
Hong Seung-Jae
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Abstract
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SAPHO syndrome is a rare inflammatory, pseudoinfectious disease. Initially it was an acronym for Syndrome Acne Pustulosis Hyperostosis Osteitis, and the meaning of S was later changed to synovitis. It occurs predominantly in children and adults and is not common over 60 years. The most common clinical presentation is osteoarticular involvement at the anterior chest wall and skin manifestations may be evident, but it could occur years earlier or develop later. We report on two cases of mother and daughter. A 51-year-old female was diagnosed with SAPHO syndrome with costochondritis and palmoplantar pustulosis. Five years later, her 31-year-old daughter presented with similar skin manifestations of the hand and foot.
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KEYWORD
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SAPHO syndrome, Acquired hyperostosis syndrome, Palmoplantaris pustulosis
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